Barely Significant
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Extracellular vesicles as a liquid biopsy for amyotrophic lateral sclerosis: a systematic review and meta-analysis.

J Transl Med · 2026 · PMC13386653 · PMID 42458453

1
hedged sentence
0.0520
closest p · 1.0× alpha
0.0520
boldest claim

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almost reached statistical significancep = 0.052so close (0.05 < p ≤ 0.1)
We removed this outlier in a subgroup analysis, and the pooled effect increased (SMD = 1.87) and almost reached statistical significance ( p = 0.052).

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