Evaluation of Immune Gene Expression Reveals Immunomodulatory Activity of Chlorella vulgaris in a Mouse Model.

Biochem Genet · 2026 · PMC13388645 · PMID 41236687

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borderline significantno p-value reported

Additionally, 4 genes exhibited borderline significant upregulation (fold change 1.8–2.0), such as Mx1 (1.95), Nfkbia (1.95), Tnf (1.94), and Stat3 (1.92), as shown in Table 2 .

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borderline significanceno p-value reported

Using a fold change threshold of > 2.0 for significant upregulation and 1.8–2.0 for borderline significance, a total of 7 immune-related genes were significantly upregulated (fold change > 2.0), including Tlr7 (4.64), Tlr9 (3.04), Mpo (2.59), Tyk2 (2.57), Stat1 (2.13), Tlr6 (2.05), and Irf7 (2.03).

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