Tryptophan metabolism in tumor immune escape: mechanisms, cellular crosstalk, and therapeutic opportunities.

Front Immunol · 2026 · PMC13388789 · PMID 42488641

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highly significantno p-value reported

This finding is highly significant because it broadens the biological role of tryptophan metabolism beyond immune regulation and places it within the larger framework of stress adaptation and metabolic resilience.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.