Targeting arginine metabolism reverses bone immunosuppressive microenvironment and metastasis in ARID1A-deficient triple negative breast cancer.

Nat Commun · 2026 · PMC13389217 · PMID 42191692

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highly significantno p-value reported

Significantly, among the top genes with the highest mutation rates we detected, mutations in ARID1A alone manifested a highly significant association with bone metastasis (Fig. 1B ).

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