Molecular Epidemiological Analysis of Carbapenem-Resistant Hypervirulent Klebsiella Pneumoniae in Cangzhou Central Hospital from 2021 to 2024.

According to bacterial resistance results in 2021, KP showed significantly higher resistance to carbapenems compared to that before 2018, which, despite a decreasing trend in recent years, still exceeds 20%, indicating challenges in most antibiotic treatments for KP. 2 Based on its virulence characteristics, KP can be classified into the classical KP and hypervirulent KP(hvKP), with the latter being a highly invasive variant of KP that can cause purulent abscesses, i

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