Comparison of surgical safety among different comprehensive treatment models for adenocarcinoma of esophagogastric junction: a single-center cohort study.

Background The incidence of adenocarcinoma of the esophagogastric junction (AEG) has shown an increasing trend both in Western and Asian countries in recent years [ 1 – 3 ], and the GLOBOCAN 2018 database showed that most of the global estimated AEG cases occurred in East Asia in 2018 [ 4 ].

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Furthermore, patients who underwent resection following nCRT demonstrated a significantly higher severity of postoperative complications, with a notable trend toward an increased incidence of anastomotic leakage compared with the surgery-first and NAC groups.

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