Barely Significant
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Galectin-3 inhibitor selvigaltin dosed therapeutically <i>in vivo</i> in a rabbit model of metabolic syndrome induced by high-fat diet: effects on rabbit differentiated adipocytes.

Front Physiol · 2026 · PMC13391330 · PMID 42495707

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an increasing trendp<0.05actually significant
In vivo selvigaltin treatments showed an increasing trend across all doses, with the highest value observed at 0.3 mg/kg (55.51 ± 8.04; p<0.05 vs both RD+Veh and HFD+Veh).

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While SDH activity showed a significant change in the HFD+Veh group, normalized by higher doses of selvigaltin, ATP production did not quite reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.