a decreasing trendP < 0.01
With increasing SPISE tertiles, BMI, TC, TG, LDL-C, and glucose levels showed a decreasing trend, whereas HDL-C increased progressively (all P < 0.01). 3.2 Association between SPISE and left main and/or three-vessel disease Table 1 shows the cross-sectional associations of SPISE with left main and/or three-vessel disease.