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Reduced CH25H expression defines a high membrane fluidity, trogocytosis active state in colon cancer stem cells.

Front Cell Dev Biol · 2026 · PMC13391522 · PMID 42495718

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Consistent with our findings in Caco-2 spheroids, CSCs exhibited increased Wnt target gene expression and reduced STAT1 target gene scores, accompanied by a decreasing trend in CH25H expression ( Supplementary Figures 7A,B ).

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