Pharmacovigilance signal detection of central nervous system demyelinating diseases following human papillomavirus vaccination: data mining and signal analysis based on the VAERS database.

Through a multidimensional analysis of the VAERS database, this study identified disproportional reporting signals for non-infectious myelitis and encephalomyelitis following HPV vaccination; among the study population, such reporting characteristics were more pronounced in females and individuals aged 9–26 years, and the incidence of these adverse events exhibited a decreasing trend over time.

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