Timed secreted proteomes reveal regulation of hepatokines by the liver circadian clock.

Nat Commun · 2026 · PMC13392424 · PMID 42230628

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highly significantno p-value reported

Most apolipoproteins tended to be secreted more at ZT8 (exceptions: APOA5, APOL7C, and APOL9B), and APOB and APOC4 were highly significant (Fig. 2f ).

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