Mitomycin C potentiates metronidazole activity in resistant Trichomonas vaginalis through suppression of thioredoxin reductase.

Int J Parasitol Drugs Drug Resist · 2026 · PMC13393407 · PMID 42476011

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an increasing trendno p-value reported

Moreover, combination treatment significantly enhanced inhibition compared with MMC monotherapy, while inhibitory effects also showed an increasing trend relative to MTZ monotherapy ( Fig. 5 B).

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