Principal component analysis (PCA) revealed close clustering of biological replicates within each group and an overall trend toward separation between the Control and GelMA/dECM@MnO 2 -GA groups in transcriptomic space ( Fig. 7 A).
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A xenogeneic developmental matrix hydrogel with MnO<sub>2</sub>-gallic acid enables spatiotemporal immunometabolic reprogramming and endochondral bone repair in steroid-associated osteonecrosis.
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