ApoE- and Cfh-deficient mice exhibit structural and molecular features of human early-intermediate retinal degeneration.

Animal Model Exp Med · 2026 · PMC13394217 · PMID 42383569

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46 , 47 , 48 , 49 A pro‐inflammatory molecular profile was evident, with overexpression of Mmp9 (a gene linked to exudative AMD) and an increasing trend in MMP activity that was not statistically significant, suggesting enhanced ECM turnover contributing to BM pathology.

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