Systematic investigation of pre-processing and feature extraction techniques in medical image analysis.

The analysis demonstrated that the optimized configurations significantly outperformed the lowest-performing configuration in all the cases, with highly significant p-values for the H&E-stained dataset ( p = 1.94 × \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${10}^{-

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