Paeoniflorin alleviates CKD-associated constipation by modulating TPH1/AHR-related signaling and suppressing NLRP3/GSDMD-mediated pyroptosis.

Front Pharmacol · 2026 · PMC13396008 · PMID 42499504

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a decreasing trendno p-value reported

Although the linaclotide group showed a decreasing trend in collagen deposition, the difference was not statistically significant.

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