Barely Significant
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Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIV<sub>mac251</sub> acquisition in vaccinated macaques.

Cell Rep Med · 2026 · PMC13400162 · PMID 42302793

Europe PMCDOI
1
hedged sentence
0.1600
closest p · 3.2× alpha
0.1600
boldest claim

The sentences

a weak trendp = 0.16not close (p > 0.1)
However, there was only a weak trend toward decreased virus acquisition in the vaccine/S-IVR group compared with the vaccinated-only group after the first ( p = 0.16; Figure 1 K) and second rounds of challenge exposures ( p = 0.19; Figure 1 L), likely due to the study’s limited power.

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