GWAS of extended prescription analgesic use identifies genetic loci in chronic pain.

Nat Commun · 2026 · PMC13402304 · PMID 42209495

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hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

modestly significantP < 4.8 × 10 − 5actually significant

Migraine showed modestly significant genetic correlations (Bonferroni-corrected P < 4.8 × 10 − 5 ) with chronic pain duration and susceptibility ( r g > |0.5 | ).

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