Chenodeoxycholic acid restrains tumor growth via TGR5-dependent type 1 dendritic cells cross-priming.

Signal Transduct Target Ther · 2026 · PMC13402744 · PMID 42503514

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highly significantno p-value reported

In the TCGA datasets for skin cutaneous melanoma (SKCM), we observed a highly significant positive correlation between MHC I molecules (HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, and HLA-H) and TGR5 (Fig. 7p ).

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