Hybrids of Benzenesulfonamide Oxadiazole Derivatives with Dual CA II and COX-2 Inhibitory Activity Demonstrating Antiglaucoma and Anti-inflammatory Action: Synthesis, In Silico Insights, and In Vitro and In Vivo Bioevaluation.

J Med Chem · 2026 · PMC13403231 · PMID 42387821

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 0.001actually significant

Nevertheless, a highly significant pharmacological effect ( P < 0.001) was observed at subsequent time intervals under the present experimental conditions.

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