Risperidone long-acting in-situ microimplant following a brief oral risperidone lead-in in the acute inpatient management of manic episodes with psychotic symptoms in non-adherent patients with schizoaffective disorder: a retrospective, uncontrolled real-world study.

Ann Gen Psychiatry · 2026 · PMC13403579 · PMID 42210281

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highly significantno p-value reported

For YMRS, all prespecified contrasts from admission to day 28 remained highly significant after Holm–Bonferroni correction, whereas the contrast between day 28 and day 42 remained non-significant, confirming rapid early improvement followed by stabilisation.

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