Fibrillarin-mediated 2'-O-methylation serves as a translation brake on uncapped enterovirus RNA.

PLoS Pathog · 2026 · PMC13405287 · PMID 42475391

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likely to be significantno p-value reported

Given the small effects, the lack of real biological replicates, and the failure to apply standards set out by MIQE, none of these changes in gene expression due to FBL knockdown or EV71 infection are likely to be significant or real.

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