N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Antioxidants (Basel) · 2026 · PMC13405467 · PMID 42510611

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highly significantno p-value reported

applied the same regimen prospectively to 120 women with endometriosis and documented highly significant improvements in dysmenorrhea, dyspareunia, and chronic pelvic pain, together with reductions in NSAID use, mean endometrioma diameter, and CA125 [ 58 ].

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a positive trendno p-value reported

In the NAC group, granulosa cell expression of Bcl-2, Bax, and Caspase-3 showed favorable non-significant trends, consistent with a positive trend for embryo quality.

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