Identification of von Willebrand Factor-Enriched Small Extracellular Vesicles as a Blood-Based Biomarker for the Detection of Head and Neck Squamous Cell Carcinoma.

Cancers (Basel) · 2026 · PMC13406140 · PMID 42512401

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In patients aged ≥ 60 years, sEV-vWF levels also showed an increasing trend in HNSCC compared with benign, although this did not reach statistical significance ( p = 0.0897), likely due to the limited number of benign samples in this age group ( n = 4) ( Figure S3A ).

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