An increasing trend was noted for four of the pro-inflammatory molecules, mainly IL-6, IL-8, IFN-γ and TNF-α, extending above the assay-specific reference intervals in the longer-duration group, suggesting a possible increase in systemic inflammation, which has been associated in previous studies with long-term T2D complications as demonstrated by available evidence [ 4 ].
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Cytokine Profiles in Patients with Type 2 Diabetes Across Different Durations of the Disease: An Exploratory Cross-Sectional Study.
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