Exogenous Heat Shock Proteins in Oncology: Biological Roles and Clinical Implications.

Cancers (Basel) · 2026 · PMC13406738 · PMID 42512385

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highly significantno p-value reported

GRP78/BiP (HSPA5) and GRP94 (HSP90B1) are significantly elevated in glioblastoma compared to normal brain tissue and early stages of gliomas, indicating an association with tumor progression [ 34 ], and HSPB1 or HSP27 is a highly significant predictor in the context of patient survival [ 34 ].

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