Metabolomic Alterations Associated with Adjunctive Hydrogen Gas Inhalation During Concurrent Chemoradiotherapy in Locally Advanced Head and Neck Cancer: A Pilot Study.

Cancers (Basel) · 2026 · PMC13407243 · PMID 42512258

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a decreasing trendno p-value reported

A decreasing trend in tetrahydrodeoxycorticosterone was also observed following CCRT ( Figure 3 f), which may be associated with changes in steroid-related metabolism; however, this observation was supported by a limited number of mapped metabolites, and its biological significance remains unclear and should be interpreted cautiously [ 30 ].

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