Ultrasonic-Microwave-Assisted Extraction of Flavonoids from Citri Reticulatae Pericarpium and Antioxidant Evaluation of Three Purified Flavonoid Compounds.

The quadratic model for the extraction rate, derived from the response surface methodology through multiple regression analyses of the experimental data, is expressed as follows: Flavonoids Yield = −200.7803 + 0.3938 B + 0.0406 C + 1.0432 D + 2.0325 E + 0.0014 BC –0.0002 BD – 0.0015 BE – 0.0016 CD – 0.0031 CE – 0.0034 DE – 0.0003 B 2 – 0.0050 C 2 – 0.0073 D 2 − 0.0066 E 2 Variance analysis revealed that the quadratic model was highly significant, whereas the lack-of-fit error term was not significant ( Table 2 ).

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