highly significantp < 0.001
While there were no significant main effects for feeding paradigm ( χ 2 (2) = 0.58, p = 0.746) or light cycle ( χ 2 (1) = 0.29, p = 0.589), we observed a highly significant three-way shift x feeding x light cycle interaction ( χ 2 (40) = 184.86, p < 0.001), indicating that the impact of circadian disruption on body weight was dependent upon both the specific feeding regimen and the cumulative duration of the intervention.