VEGF Expression in Head and Neck Squamous Cell Carcinoma: Association with TNM Staging and Tumor Progression.

Curr Issues Mol Biol · 2026 · PMC13409531 · PMID 42510965

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

a trend toward significancep = 0.061so close (0.05 < p ≤ 0.1)

Multivariate logistic regression (3 variables, 32 events; EPV = 10.7, meeting the conventional ≥ 10 threshold) demonstrated that lymph node involvement (N+) remained a significant predictor of high VEGF expression (OR = 2.85; 95% CI: 1.12–7.24; p = 0.028), while tumor stage showed a trend toward significance ( p = 0.061).

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