An Interpretable Four-Gene Cell-Cycle Signature Links Malignant Progression to Adverse Survival in Adult Primary Diffuse Glioma: A CGGA Transcriptome Study.

Genes (Basel) · 2026 · PMC13409654 · PMID 42510873

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highly significantno p-value reported

CDCA3 showed a slightly smaller mean difference than the DEG effect-size cut-off but was retained because it showed a highly significant monotonic grade-associated pattern and has prior literature support as a mitotic regulator and glioma biomarker [ 10 ].

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