Intestinal epithelial PIEZO1 regulates macrophage-to-myofibroblast transition via epithelial-derived TGF-α signaling in Crohn's disease.

Cell Commun Signal · 2026 · PMC13411382 · PMID 42210253

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a decreasing trendno p-value reported

Notably, TGF-α expression was significantly reduced in colonic tissues from CKO mice, accompanied by a decreasing trend in circulating TGF-α levels (Fig. 6 E-F and Supplementary Materials 1: Fig.

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