MTUS2-AS1 suppression promotes DDX5 protein degradation to enhance the sensitivity of PARP inhibitors in BRCA-wild triple negative breast cancer.

Int J Biol Sci · 2026 · PMC13412408 · PMID 42524562

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a decreasing trendno p-value reported

The results showed that DNA synthesis in TNBC cells exhibited a decreasing trend upon silencing MTUS2-AS1, suggesting that MTUS2-AS1 knockdown may suppress TNBC cells proliferation to a certain extent (Supplementary Figure S3 C).

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