Perspective for CAR T-Cell Therapy in Underrepresented Populations: A Hypothesis-Generating CD19 Genomic Analysis.

J Pers Med · 2026 · PMC13412835 · PMID 42506070

Europe PMC DOI

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 0.00001actually significant

Hardy–Weinberg equilibrium analysis for rs2904880 revealed highly significant deviation from expected genotype counts ( χ 2 = 161.4, df = 1, p < 0.00001), characterized by a marked heterozygote deficit (observed 271 [22.66%] vs. expected 428.36 [35.82%]) and a reciprocal homozygote excess.

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