Bile Acid Metabolism in Gout Pathogenesis from Gut-Liver-Joint Crosstalk to Therapeutic Opportunities.

Metabolites · 2026 · PMC13413603 · PMID 42506417

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a decreasing trendno p-value reported

Although the direction of change in total bile acid (TBA) levels varies across studies, most evidence tends to support a decreasing trend, which may result from impaired hepatic synthesis capacity, intestinal reabsorption defects, or systemic inflammation-induced suppression of bile acid transporters [ 30 ].

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