Interestingly, the emergence of new variants in the L1C.5, L1C.2, and L1H have been reported as an increasing trend in variant circulation patterns in sequence-surveillance datasets, as recently illustrated by ( https://Mshmp.Umn.Edu/PRRS-Variant-Monitoring ) (accessed on 15 May 2026) [ 43 ].
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Geographic Distribution and ORF5 Diversity of PRRSV-2 Variants in Midwestern U.S. Diagnostic Submissions, 2023-2025.
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