Regarding Caspase-3, a highly significant increase in immunoreactivity was determined after α-PHP treatment at all tested concentrations (50 μM, 100 μM, and 200 μM) as well as in the neurosphere exposed to EtOH, compared to control and vehicle groups.
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The MDPV Derivative α-PHP Regulates Cellular Differentiation and Triggers Apoptotic Cell Death and Ultrastructural Changes in Murine 3D Neurospheres.
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