In NSCLC, CD4 + Tcm cell frequencies show an increasing trend ( 80 ), and elevated frequencies of CD8 + Tcm and Tem cells have also been reported ( 18 ); similarly, increased CD8 + Tcm and Tem subsets have been described in head and neck squamous cell carcinoma ( 81 , 82 ).
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Distribution and function of human long-lasting T cells in aging and non-small cell lung cancer.
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