Effects of Non-Nutritive Artificial Sweeteners on Gut Microbiota and Host Metabolism and Health-Related Outcomes: A Review.

In adults with overweight or obesity, fruit-filled biscuits sweetened with neotame reduced the postprandial incremental area under the curve for insulin (insulin iAUC) compared with sucrose, whereas postprandial glucose showed only a decreasing trend without statistical significance and no significant differences were observed in composite appetite score, explicit liking, implicit wanting, ghrelin, GLP-1, or pancreatic polypeptide [ 74 ].

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