highly significantp < 0.001
Results were consistent with the primary analysis: the linear Time × Study interaction was b = 0.557, SE = 0.191, p = 0.004, and the quadratic interactions remained highly significant (Time × Study: b = 3.438, SE = 0.459, p < 0.001; Time 2 × Study: b = −3.344, SE = 0.489, p < 0.001).