Frequency-selective thymic programming by early-life cold stress requires interferon regulatory factor 5.

Front Immunol · 2026 · PMC13416564 · PMID 42529352

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an increasing trendno p-value reported

The results showed that, compared to Ctrl, the 2× stress exhibited no significant change in Irf4 levels, whereas Irf5 levels showed an increasing trend at 1 h and a significant decrease by 24 h post-stress.

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