Organ-on-a-Chip and Microfluidic Plant Cell Culture Systems: The Next Frontier for Controlled Secondary Metabolite Production and Real-Time Metabolomic Monitoring.

Surface Chemistry and Biocompatibility for Plant Cells An important and often overlooked parameter in the fidelity of experiments in microfluidic biology is the interface formed between the walls of the microchannel and the biological materials studied; this becomes highly significant when the biological materials are plant cells, which possess complex cell walls made up of biopolymer-based materials, chemically active surfaces, and mechanical sensitivity requiring a high level of compatibility with protocols developed for mammalian cell culture.

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