Serological epidemiology of hepatitis B virus and vaccine-induced immune dynamics in 58,169 children in Wuhan, China (2019-2025): a cross-sectional analysis of waning immunity and adolescent susceptibility.

Virol J · 2026 · PMC13419023 · PMID 42210247

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an increasing trendno p-value reported

Median titers [IQR] were 178.80 [50.59, 739.62] for males and 182.94 [48.47, 737.25] for females.The HBsAb reactive rate in children showed an increasing trend from within 24 h after birth up to 1 year of age, rising from 69.13% within 24 h to a peak of 98.48% in the 7–12-month age group.

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