Functional PET imaging of gut microbiota with [18F]fluorodeoxyglucose, [18F]fluorodeoxysorbitol and [11C]choline reflects Clostridia and Lactobacillales abundance in caecum and small intestine and host metabolic interactions.

Eur J Nucl Med Mol Imaging · 2026 · PMC13421236 · PMID 42286318

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Highly significant distances between untreated, antibiotic and probiotic treated groups were observed in the intestinal tracts emerging as main bacterial functional sites from our PET images, namely the caecum for [ 18 F]FDG and [ 18 F]FDS and the proximal and central small gut for [ 11 C]cho (Fig. 6 b, Supplementary Information S1 a, S1 c, S1 g).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Functional PET imaging of gut microbiota with [&lt;sup&gt;18&lt;/sup&gt;F]fluorodeoxyglucose, [&lt;sup&gt;18&lt;/sup&gt;F]fluorodeoxysorbitol and [&lt;sup&gt;11&lt;/sup&gt;C]choline reflects Clostridia and Lactobacillales abundance in caecum and small intestine and host metabolic interactions.

The sentences

Functional PET imaging of gut microbiota with [<sup>18</sup>F]fluorodeoxyglucose, [<sup>18</sup>F]fluorodeoxysorbitol and [<sup>11</sup>C]choline reflects Clostridia and Lactobacillales abundance in caecum and small intestine and host metabolic interactions.