Ferroptosis in retinal pigment epithelial cells: Current status and future developments.

Indian J Ophthalmol · 2026 · PMC13422901 · PMID 41669765

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Studies have found that iron accumulation in RPE cells is highly significant in both dry and wet AMD.[ 41 ] The ferroptosis process triggered by iron accumulation impairs the function of RPE cells or even leads to their death, disrupting the normal structure and function of the retina.

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