Risk factors and clinical impact of bone pain in patients with multiple myeloma - A prospective interdisciplinary study.

Patients with bone pain at study inclusion demonstrated a distinct bone-centric disease pattern, characterized by highly significant increases in osteolytic lesions with structural instability risk (25% vs. 11%, p = 0.0001) and higher prevalence of CRAB-B already present at ID (90% vs. 78%, p = 0.003).

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