One-dimensional palladium MOF as VEGFR2 and colchicine binding inhibitors with potential anticancer and anti-inflammatory activities: synthesis and molecular investigation.

Although Pd-MOF produced a highly significant downregulation of VEGFR2 gene expression in A549 cells compared with the untreated control ( p < 0.00001; Fig. 7 D), its inhibitory potency remained considerably weaker than that of the reference drug, sorafenib.

also in 132,142 other papers