Combination of proton-pump inhibitor and anti-CD3 F(ab')<sub>2</sub> for islet neogenesis and immune modulation in type 1 diabetes.

Immunother Adv · 2026 · PMC13426313 · PMID 42540695

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an increasing trendno p-value reported

Following combination therapy, CD3 + CD8 + and CD3 + CD4 + T-cell frequencies were significantly reduced, and Treg frequency showed an increasing trend ( Fig. 6a–c ).

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Combination of proton-pump inhibitor and anti-CD3 F(ab')&lt;sub&gt;2&lt;/sub&gt; for islet neogenesis and immune modulation in type 1 diabetes.

The sentences

Combination of proton-pump inhibitor and anti-CD3 F(ab')<sub>2</sub> for islet neogenesis and immune modulation in type 1 diabetes.