Impact of secretome containing extracellular vesicles from human induced pluripotent stem cell-derived cardiomyocytes.

Regen Ther · 2026 · PMC13427465 · PMID 42541290

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an increasing trendno p-value reported

Compared to the Day 16 samples, the Day 25 samples showed statistically significant increases in the expression of TNNT2 , CACNA1C, KCNH2, KCNJ2 , and SCN5A , and an increasing trend was also observed for HCN4 ( Fig. 1 f).

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highly significantno p-value reported

The identification of specific miRNAs, such as miR-133b, miR-208b, and miR-499b, in the Day 25 EV fraction was highly significant.

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