The quest for the best: manual, atlas- and spatial prior-based delineation of locus coeruleus.

Neuroimage Clin · 2026 · PMC13427573 · PMID 42492140

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highly significantno p-value reported

Conversely, PD* showed the most substantial deviation of all metrics, characterized by a continuous and highly significant lifespan increase (Left: +0.587 Z, eff = 0.14; Right: +0.571 Z, eff = 0.15; P FDR < 6.6 × 10 −11 ).

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